2010 Louisville Slugger/NFCA Division I All-America Teams
First Team
| Position | Name | School |
| Pitcher | Kenzie Fowler | Arizona |
| Pitcher | Danielle Lawrie | Washington |
| Pitcher | Jen Mineau | Fordham |
| Catcher | Chelsea Bramlett | Mississippi State |
| First Base | Meredith Hackett | Illinois |
| Second Base | Jen Yen | Georgia Tech |
| Third Base | Melissa Gonzalez | Hawai'i |
| Shortstop | Katelyn Boyd | Arizona State |
| Outfield | Alissa Haber | Stanford |
| Outfield | Brittany Lastrapes | Arizona |
| Outfield | April Setterlund | Boston University |
| UT/P | Megan Langenfeld | UCLA |
| UT/Non-P/DP | Niki Williams | Washington |
| At-Large/UT-P | Valerie Arioto | Cal |
| At-Large/2B | GiOnna DiSalvatore | UCLA |
| At-Large/SS | Jenn Salling | Washington |
| At-Large/OF | Kristen Shortridge | Louisiana State |
| At-Large/UT-P | Danielle Spalding | North Carolina |
Second Team
| Position | Name | School |
| Pitcher | Blaire Luna | Texas |
| Pitcher | Keilani Ricketts | Oklahoma |
| Pitcher | Jordan Taylor | Michigan |
| Catcher | Stacie Chambers | Arizona |
| First Base | Dorian Shaw | Michigan |
| Second Base | Amber Flores | Oklahoma |
| Third Base | Maggie Viefhaus | Michigan |
| Shortstop | K'Lee Arredondo | Arizona |
| Outfield | Kelly Majam | Hawai'i |
| Outfield | Taylor Schlopy | Georgia |
| Outfield | Francesca Enea | Florida |
| UT/P | Charlotte Morgan | Alabama |
| UT/Non-P/DP | Jessica Shults | Oklahoma |
| At-Large/2B | Kayla Braud | Alabama |
| At-Large/3B | Alisa Goler | Georgia |
| At-Large/C | Meagan May | Texas A&M |
| At-Large/UT-P | Nikki Nemitz | Michigan |
| At-Large/C | Melissa Roth | Louisville |
Third Team
| Position | Name | School |
| Pitcher | Whitney Kiihnl | Lipscomb |
| Pitcher | Toni Paisley | East Carolina |
| Pitcher | Sara Plourde | Massachusetts |
| Catcher | Sam Marder | Ohio State |
| First Base | Renae Sinkler | Creighton |
| Second Base | Kara Nelson | Illinois State |
| Third Base | Abby Olson | Illinois State |
| Shortstop | Lauren Grill | Mississippi |
| Outfield | Raven Chavanne | Tennessee |
| Outfield | Lauren Lindsay | Tulsa |
| Outfield | Rhea Taylor | Missouri |
| Designated Player | Hope Rush | Georgia Tech |
| Utility | Miranda Dixon | Arkansas |
| At-Large | Samantha Beasley | San Diego State |
| At-Large | Stephanie Brombacher | Florida |
| At-Large | Kat Dotson | Tennessee |
| At-Large | Kelsi Dunne | Alabama |
| At-Large | Katie Fleury | Notre Dame |
